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HRID336099

反应详情

EQUATION

反应方程式

HRID 336099 的结构方程式

REACTANTS

反应物

2
结构：O=[N+]([O-])c1ccc(S(=O)(=O)Cl)c([N+](=O)[O-])c1
HCID74255

Benzenesulfonyl chloride, 2,4-dinitro-

C6H3ClN2O6S

结构：[O-][n+]1ccccc1O
HCID178526252

未命名化合物

PRODUCTS

生成物

1
结构：O=c1ccccn1OS(=O)(=O)c1ccc([N+](=O)[O-])cc1[N+](=O)[O-]
HCID54767382

未命名化合物

收率 31%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：c1ccncc1
溶剂HCID1049

Pyridine

C5H5N

PROCEDURE

实验过程

2-Hydroxypyridine-1-oxide (0.5 g, 4.5 mmol) was reacted with 2,4-dinitrobenzenesulfonyl chloride (1.32 g, 5.0 mmol) in 40 mL of pyridine to afford PZBG-1d in 31% yield (0.48 g, 1.4 mmol). 1H NMR (500 MHz, CDCl3) δ=8.96 (d, J=2.3 Hz, 1H), 8.42 (dd, J1=9.2 Hz, J2=2.3 Hz, 1H), 7.68 (dd, J1=6.9 Hz, J2=1.7 Hz, 1H), 7.50 (dt, J1=7.5 Hz, J2=2.3 Hz, 1H), 7.06 (d, J=8.1 Hz, 1H), 6.82 (dd, J1=9.2 Hz, J2=1.8 Hz, 1H), 6.35 (dt, J1=6.9 Hz, J2=1.8 Hz, 1H). 13C NMR (100 MHz, CDCl3) δ=157.0, 155.6, 140.5, 135.1, 129.6, 124.0, 122.9, 116.0, 106.6.

WORKUP

后处理

  1. customto afford PZBG-1d in 31% yield (0.48 g, 1.4 mmol)