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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 336173Generated: October 29, 2026

HCID 78322881, compound → HCID 86711290, compound

https://huagongshe.com/reaction/336173

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 78322881HCID 78322881—
ReactantHCID 86711289HCID 86711289—
ProductHCID 86711290HCID 8671129052%

Reaction Steps

In accordance with Example 10, except that the (R)-tert-butyl (5-(4-amino-6-bromo-5-(quinolin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)penta-1-en-3-yl)carbamate (994 mg) obtained in Reference Example 10 was used in place of the (S)-tert-butyl (1-(4-amino-6-bromo-5-(quinolin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)but-3-en-2-yl)carbamate obtained in Example 10, the title compound (439 mg) (yield: 52%) was obtained as a yellow solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08889666B2
Source datasetuspto-grants-2014_11
ORD IDord-32c221b04b0c45d7aeb3f3abd409da04
Source noteuspto-grants-2014_11