HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 78322881, compound → HCID 86711290, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 78322881 | HCID 78322881 | — |
| Reactant | HCID 86711289 | HCID 86711289 | — |
| Product | HCID 86711290 | HCID 86711290 | 52% |
Reaction Steps
In accordance with Example 10, except that the (R)-tert-butyl (5-(4-amino-6-bromo-5-(quinolin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)penta-1-en-3-yl)carbamate (994 mg) obtained in Reference Example 10 was used in place of the (S)-tert-butyl (1-(4-amino-6-bromo-5-(quinolin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)but-3-en-2-yl)carbamate obtained in Example 10, the title compound (439 mg) (yield: 52%) was obtained as a yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08889666B2 |
| Source dataset | uspto-grants-2014_11 |
| ORD ID | ord-32c221b04b0c45d7aeb3f3abd409da04 |
| Source note | uspto-grants-2014_11 |