HCID 25255976, compound → HCID 68775324, compound

Participants

Reaction Conditions

Reaction Steps

Stannous chloride dihydrate (285 mg; 1.26 mmol; 5 eq.) was added to a solution of Example 12 (105 mg; 0.25 mmol; 1 eq.) in EtOH (20 mL) and the resulting mixture was stirred at 70° C. for 3 hours, then at room temperature for 16 hours. The solution was diluted with sat. aq. NaHCO3 and extracted with ethyl acetate. The combined organic layer was washed with brine, dried over magnesium sulfate and concentrated in vacuo to afford the title compound (97 mg, 100%) as a yellow solid.

Provenance & Evidence