HuagongsheHuagongshe Chemistry Print Report · For research reference only
Oxalyl chloride → HCID 25256566, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Oxalyl chloride | HCID 65578 | — |
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | N-Hydroxy-2-methoxy-benzamidine | HCID 4652214 | — |
| Reactant | 3-Methoxy-4-(2-methylphenyl)benzoic acid | HCID 18001076 | — |
| Product | HCID 25256566 | HCID 25256566 | — |
Reaction Steps
Oxalyl chloride (126 μL; 1.49 mmol; 3 eq.), Intermediate 27 (120 mg; 0.5 mmol; 1 eq.), Intermediate 1 (82 mg; 0.5 mmol, 1 eq.) and DIEA (256 μL; 1.49 mmol; 3 eq.) were reacted according to general procedure 2. Purification by precipitation from DCM/n-pentane afforded the title compound as a brown solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08889668B2 |
| Source dataset | uspto-grants-2014_11 |
| ORD ID | ord-bb8fca81569a4cddb674e06a2f90b445 |
| Source note | uspto-grants-2014_11 |