HCID 56923707, compound → HCID 178519924, compound

HRID 336357Notes

Reaction equation

HRID 336357 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([CH:25]=[CH:26][CH:27]=1)[CH2:5][C@H:6]1[CH2:11][CH2:10][CH2:9][CH2:8][N:7]1[C:12]([C:14]1[C:23]([OH:24])=[N:22][C:21]2[C:16](=[CH:17][CH:18]=[CH:19][CH:20]=2)[N:15]=1)=[O:13].C([C@H](C(N)CC1C=CC=C(Cl)C=1)C(O)=O)(OC(C)(C)C)=O>>[Cl:1][C:2]1[CH:3]=[C:4]([CH:25]=[CH:26][CH:27]=1)[CH2:5][C@@H:6]1[CH2:11][CH2:10][CH2:9][CH2:8][N:7]1[C:12]([C:14]1[C:23]([OH:24])=[N:22][C:21]2[C:16](=[CH:17][CH:18]=[CH:19][CH:20]=2)[N:15]=1)=[O:13]

Participants

3

Reactant 2

HCID 56923707HCID 56923707, compoundHCID 178519923HCID 178519923, compound

Product 1

HCID 178519924HCID 178519924, compound

Procedure

Compound 7-8 (S isomer) was prepared analogous to the preparation of Compound 7-7 beginning from Boc-(R)-3-amino-4-(3-chlorophenyl)butyric acid.

Sources & evidence

ORD record
ord-c7b3c6dc494a4cfeb42cb0382f228e73
Source dataset
uspto-grants-2014_11
Patent number
US08889683B2

Reaction notes

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