反应详情

115 mL bromine hydro acid was added to 9.5 g 5-phenyl-2H-(1,2,4)triazol-3-ylamine and 12.3 g sodiumnitrite at −5° C. The reaction was warmed to RT and refluxed for 20 min. Then the mixture was cooled and basicfied with sodiumdicarbonate and extracted with ethyl acetate. The organic layer was dried and evaporated to give 11 g of the desired product.

1. temperaturerefluxed for 20 min
2. temperatureThen the mixture was cooled
3. extractionextracted with ethyl acetate
4. customThe organic layer was dried
5. customevaporated