Sodium borohydride → HCID 59186318, compound

Participants

Reaction Steps

To a solution of 4-(5-(3-(methylsulfonyl)phenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-ylamino)benzaldehyde (450 mg, 1.15 mmol) in tetrahydrofuran was added sodium borohydride (22 mg, 0.57 mmol) at 24° C. After 3 hr, the reaction mixture filtered through Celite. The solvent was removed in vacuo to provided the crude product which was purified by preparative thin layer chromatography to afford the desired product (300 mg, 67% yield). LCMS (ESI) m/z: 395.1.

Provenance & Evidence