HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 2,2-Dimethyl-propionic acid (R)-2-amino-3-(4-methoxy-benzylsulfanyl)-propyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Pivaloyl chloride | HCID 62493 | — |
| Reactant | (S)-2-t-butoxycarbonylamino-3-(4-methoxy-benzylsulfanyl)-propanol | HCID 14539894 | — |
| Product | 2,2-Dimethyl-propionic acid (R)-2-amino-3-(4-methoxy-benzylsulfanyl)-propyl ester | HCID 59543057 | — |
Reaction Steps
(S)-2-t-butoxycarbonylamino-3-(4-methoxy-benzylsulfanyl)-propanol prepared in Step C, trimethylacetylchloride and HCl (4 N dioxane solution) were reacted according to the same procedures as Steps D and E of Preparation 31 consecutively to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08889691B2 |
| Source dataset | uspto-grants-2014_11 |
| ORD ID | ord-6efe245bf46944749700bb6a262b2d43 |
| Source note | uspto-grants-2014_11 |