HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylformamide → HCID 86644355, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | Morpholine | HCID 8083 | — |
| Reactant | 2,2-Dimethyl-propionic acid [(R)-2-(5-chloromethyl-7-nitro-1H-indol-2-yl)-4,5-dihydro-thiazol-4-yl]methyl ester | HCID 59542988 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | HCID 86644355 | HCID 86644355 | — |
Reaction Steps
2,2-Dimethyl-propionic acid [(R)-2-(5-chloromethyl-7-nitro-1H-indol-2-yl)-4,5-dihydro-thiazol-4-yl]methyl ester prepared in Preparation 41 and morpholine were reacted according to the same procedure as Preparation 92 except that DMF was used as the solvent instead of DMSO to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08889691B2 |
| Source dataset | uspto-grants-2014_11 |
| ORD ID | ord-fd78434dac23426eafd22d3d9e396703 |
| Source note | uspto-grants-2014_11 |