HCID 70654064, compound → HCID 178524534, compound

Participants

Reaction Steps

Next, 2,6-dibenzyloxy-5-fluoronicotinic acid (5.00 g) was dissolved in dioxane (50 mL), and 20% palladium hydroxide (50% wet, 500 mg) was added thereto and reacted under a hydrogen atmosphere for 1 hour. The palladium hydroxide was filtered through Celite from the resulting reaction product, and the solvent was evaporated to obtain a compound, i.e., 2,6-dihydroxy-5-fluoronicotinic acid (2.58 g).

Provenance & Evidence