4-Chloroaniline → HCID 53253065, compound

Participants

Reaction Steps

A mixture of 6-(4-chlorophenylsulfonyl)-8-methyl-2-(methylsulfinyl)pyrido[2,3-d]pyrimidin-7(8H)-one (1 eq) and 4-chloroaniline (1.5 eq) in toluene was refluxed overnight. After completion of the reaction (monitored by TLC) the reaction mixture was cooled to ambient temperature. The solid separated, was filtered, washed with hexane, and dried to afford the desired compound.

Provenance & Evidence