4-Chloroaniline → HCID 70895718, compound

HRID 336520Notes

Reaction equation

Cl[C:2]1[CH:7]=[CH:6][C:5]([S:8]([C:11]2[C:23](=[O:24])[N:22]([CH3:25])[C:14]3[N:15]=[C:16](S(C)=O)[N:17]=[CH:18][C:13]=3[CH:12]=2)(=[O:10])=[O:9])=[CH:4][CH:3]=1.Cl[C:27]1[CH:33]=[CH:32][C:30]([NH2:31])=[CH:29]C=1>>[CH:25]1([N:22]2[C:14]3[N:15]=[C:16]([NH:31][CH:30]4[CH2:29][CH2:27][CH2:33][CH2:32]4)[N:17]=[CH:18][C:13]=3[CH:12]=[C:11]([S:8]([C:5]3[CH:6]=[CH:7][CH:2]=[CH:3][CH:4]=3)(=[O:10])=[O:9])[C:23]2=[O:24])[CH2:4][CH2:3][CH2:2][CH2:7]1

Participants

Reactant 2

HCID 78124-Chloroaniline

HCID 67236377HCID 67236377, compound

Product 1

HCID 70895718HCID 70895718, compound

Procedure

The title compound was prepared according to the procedure of Example 3, substituting 8-cyclopentyl-2-(methylsulfinyl)-6-(phenylsulfonyl)pyrido[2,3-d]pyrimidin-7(8H)-one for 6-(4-chlorophenylsulfonyl)-8-methyl-2-(methylsulfinyl)pyrido[2,3-d]pyrimidin-7(8H)-one, and substituting cyclopentylamine for 4-chloroaniline.

Sources & evidence

ORD record: ord-2f0997fcf49646dcbeb5f702df546d09
Source dataset: uspto-grants-2014_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08889696B2

Reaction notes

Loading…