Cesium carbonate → HCID 68000648, compound

Participants

Reaction Steps

The process is performed according to the procedure described in Example 2 (step 2.7.). Starting with 0.68 g (1.42 mmol) of ethyl 5-[6-(5-bromopyridin-2-yl)-6-azaspiro[3.4]oct-2-ylcarbamoyloxymethyl]isoxazole-3-carboxylate (isomer 6′) and 0.23 g (1.70 mmol) of 4-fluorophenylboronic acid, 1.38 g (4.26 mmol) of caesium carbonate and 0.11 g (0.14 mmol) of PdCl2dppf.CH2Cl2, 0.32 g of a white solid is obtained.

Provenance & Evidence