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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 336578Generated: October 25, 2026

Tricyclo(3.3.1.1'3,7)dec-1-ylmethanol → 1-(tricyclo[3.3.1.13,7]dec-2-ylmethyl)-4-iodo-1H-pyrazole

https://huagongshe.com/reaction/336578

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTricyclo(3.3.1.1'3,7)dec-1-ylmethanolHCID 64556—
Reactant4-IodopyrazoleHCID 77022—
Reactant3,5-Dimethylpyrazole-4-boronic acid, pinacol esterHCID 16217713—
Product1-(tricyclo[3.3.1.13,7]dec-2-ylmethyl)-4-iodo-1H-pyrazoleHCID 86681258—

Reaction Steps

The title compound was prepared by substituting EXAMPLE 10A for 1-adamantanemethanol and 4-iodopyrazole for 3,5-dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole in EXAMPLE 2A.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08889675B2
Source datasetuspto-grants-2014_11
ORD IDord-83f8606d1f1c471cbee8ccf8705a7c0d
Source noteuspto-grants-2014_11