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HRID336671

反应详情

EQUATION

反应方程式

HRID 336671 的结构方程式

REACTANTS

反应物

3
结构：O=Cc1ccc(OCC(=O)O)cc1
HCID89177

Acetic acid, (4-formylphenoxy)-

C9H8O4

结构：COc1cc(N)c(C(N)=O)c(OC)c1
HCID20349016

2-Amino-4,6-dimethoxybenzamide

C9H12N2O3

结构：COc1cc(OC)c2c(=O)[nH]c(-c3ccc(O)cc3)nc2c1
HCID136038000

未命名化合物

PRODUCTS

生成物

1
结构：COc1cc(OC)c2c(=O)[nH]c(-c3ccc(OCC(=O)O)cc3)nc2c1
HCID136038018

未命名化合物

收率 21%

PROCEDURE

实验过程

2-(4-(5,7-Dimethoxy-4-oxo-3,4-dihydroquinazolin-2-yl)phenoxy)acetic acid was synthesized from 2-amino-4,6-dimethoxy-benzamide and (4-formyl phenoxy)acetic acid, using the method described for 2-(4-hydroxyphenyl)-5,7-dimethoxyquinazolin-4(3H)-one. 2-(4-(5,7-Dimethoxy-4-oxo-3,4-dihydroquinazolin-2-yl)phenoxy)acetic acid (135 mg, 21%) was isolated as an off-white solid. Selected data: MS (m/z): 357.04; MP 287-290° C.