HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Dimethylamino-1-naphthaldehyde → 2-(4-(Dimethylamino)naphthalen-1-yl)-5,7-dimethoxyquinazolin-4(3H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Dimethylamino-1-naphthaldehyde | HCID 608052 | — |
| Reactant | 2-Amino-4,6-dimethoxybenzamide | HCID 20349016 | — |
| Reactant | 5,7-dimethoxy-2-(pyridin-2-yl)quinazolin-4(3H)-one | HCID 136037998 | — |
| Product | 2-(4-(Dimethylamino)naphthalen-1-yl)-5,7-dimethoxyquinazolin-4(3H)-one | HCID 136037975 | 26% |
Reaction Steps
2-(4-(Dimethylamino)naphthalen-1-yl)-5,7-dimethoxyquinazolin-4(3H)-one was synthesized from 2-amino-4,6-dimethoxybenzamide and 4-dimethylamino-1-naphthaldehyde, using the method described for 5,7-dimethoxy-2-(pyridin-2-yl)quinazolin-4(3H)-one. 2-(4-(Dimethylamino)naphthalen-1-yl)-5,7-dimethoxyquinazolin-4(3H)-one (75 mg, 26%) was isolated as a yellow solid. Selected data: MS (m/z): 376.07; MP 269-271° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08889698B2 |
| Source dataset | uspto-grants-2014_11 |
| ORD ID | ord-dffeb83e0120442da6fddfc43e44713d |
| Source note | uspto-grants-2014_11 |