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HRID336693

反应详情

EQUATION

反应方程式

HRID 336693 的结构方程式

REACTANTS

反应物

3
结构：CN(C)c1ccc(C=O)c2ccccc12
HCID608052

4-Dimethylamino-1-naphthaldehyde

C13H13NO

结构：COc1cc(N)c(C(N)=O)cc1OC
HCID10867236

2-amino-4,5-dimethoxybenzamide

C9H12N2O3

结构：COc1cc(OC)c2c(=O)[nH]c(-c3ccccn3)nc2c1
HCID136037998

未命名化合物

PRODUCTS

生成物

1
结构：COc1cc2nc(-c3ccc(N(C)C)c4ccccc34)[nH]c(=O)c2cc1OC
HCID135939032

未命名化合物

收率 56%

PROCEDURE

实验过程

2-(4-(Dimethylamino)naphthalen-1-yl)-6,7-dimethoxyquinazolin-4(3H)-one was synthesized from 2-amino-4,5-dimethoxy-benzamide and 4-Dimethylamino-naphthalene-1-carbaldehyde, using the method described for 5,7-dimethoxy-2-(pyridin-2-yl)quinazolin-4(3H)-one. 2-(4-(dimethylamino)naphthalen-1-yl)-6,7-dimethoxy-quinazolin-4(3H)-one (159 mg, 56%) was isolated as a white solid. Selected data: MS (m/z): 376.13; MP 235.5-236.5° C.