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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 336818Generated: October 25, 2026

Benzaldehyde → 1-(3-(1h-Imidazol-1-yl)propyl)-5-phenylimidazolidine-2,4-dione

https://huagongshe.com/reaction/336818

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzaldehydeHCID 240—
Reactant1H-Imidazole-1-propanamineHCID 78736—
ReactantBenzyl isocyanideHCID 82558—
ReactantHCID 178418250HCID 178418250—
Product1-(3-(1h-Imidazol-1-yl)propyl)-5-phenylimidazolidine-2,4-dioneHCID 46181268—

Reaction Steps

The compound was synthesized starting from 3-(1H-imidazol-1-yl)propylamine 1.0 g (7.98 mmol), benzaldehyde 0.807 ml (7.98 mmol), benzylisonitrile 0.972 ml (7.98 mmol), pyidiniumchloride 0.920 and KOCN 0.648 g (7.98 mmol) as described in method 1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08889709B2
Source datasetuspto-grants-2014_11
ORD IDord-6a6efb9c2d1e4baa83497ba8bbbb9625
Source noteuspto-grants-2014_11