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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 336819Generated: October 25, 2026

Benzaldehyde → 1-(3-(5-Methyl-1h-imidazol-1-yl)propyl)-5-phenylimidazolidine-2,4-dione

https://huagongshe.com/reaction/336819

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzaldehydeHCID 240—
ReactantBenzyl isocyanideHCID 82558—
Reactant3-(5-methyl-1H-imidazol-1-yl)propan-1-amineHCID 19429483—
ReactantHCID 178418250HCID 178418250—
Product1-(3-(5-Methyl-1h-imidazol-1-yl)propyl)-5-phenylimidazolidine-2,4-dioneHCID 46181343—

Reaction Steps

The compound was synthesized starting from (3-(5-methyl-1H-imidazol-1-yl)propyl)amine 0.278 g (2 mmol), benzaldehyde 0.202 ml (2 mmol), benzylisonitrile 0.245 ml (2 mmol) pyridiniumchloride 0.231 g (2 mmol) and KOCN 0.165 g (2 mmol) as described in method 1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08889709B2
Source datasetuspto-grants-2014_11
ORD IDord-235e2fb653924bcf9c6d9a9eb1844693
Source noteuspto-grants-2014_11