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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 336820Generated: October 25, 2026

Benzaldehyde → 1-(3-(4-Methyl-1h-imidazol-1-yl)propyl)-5-phenylimidazolidine-2,4-dione

https://huagongshe.com/reaction/336820

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzaldehydeHCID 240—
ReactantBenzyl isocyanideHCID 82558—
Reactant3-(4-Methyl-1H-imidazol-1-yl)propan-1-amineHCID 15034954—
ReactantHCID 178418250HCID 178418250—
Product1-(3-(4-Methyl-1h-imidazol-1-yl)propyl)-5-phenylimidazolidine-2,4-dioneHCID 46181418—

Reaction Steps

The compound was synthesized starting from 3-(4-methyl-1H-imidazol-1-yl)propyl amine 0.250 g (1.8 mmol), benzaldehyde 0.182 ml (1.8 mmol), benzylisonitrile 0.220 ml (1.8 mmol) pyridiniumchloride 0.210 g (1.8 mmol) and KOCN 0.150 g (1.8 mmol) as described in method 1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08889709B2
Source datasetuspto-grants-2014_11
ORD IDord-9673f797cbae4f11870c5847736e9c8b
Source noteuspto-grants-2014_11