HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenol → HCID 66689398, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenol | HCID 996 | — |
| Reactant | 1-Bromo-2-Chloroethane | HCID 7849 | — |
| Reactant | HCID 66688783 | HCID 66688783 | — |
| Reactant | HCID 66689314 | HCID 66689314 | — |
| Product | HCID 66689398 | HCID 66689398 | — |
Reaction Steps
α,α-Diethyl-2-(phenylmethoxy)-benzenemethanamine (Example 266d) was converted to N-cyclopropyl-3-[3-[[1-ethyl-1-(2-hydroxyphenyl)propyl]amino]-2-oxo-1(2H)-pyrazinyl]-4-methyl-benzamide using the method described in Example 134. This phenol was alkylated with 1-bromo-2-chloroethane as described in example 167e to afford the subtitle product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08889692B2 |
| Source dataset | uspto-grants-2014_11 |
| ORD ID | ord-e6802ba7c25141bfb06bb8d33b7337e4 |
| Source note | uspto-grants-2014_11 |