HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-(2,3-dihydro-1H-inden-5-yl)-4-methoxythiophene-3-carbonitrile → 1-[5-(2,3-dihydro-1H-inden-5-yl)-4-methoxythiophen-3-yl]ethanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-(2,3-dihydro-1H-inden-5-yl)-4-methoxythiophene-3-carbonitrile | HCID 68160636 | — |
| Reactant | 1-[4-Methoxy-5-(5,6,7,8-tetrahydronaphthalen-2-yl)thiophen-3-yl]ethanone | HCID 68162295 | — |
| Product | 1-[5-(2,3-dihydro-1H-inden-5-yl)-4-methoxythiophen-3-yl]ethanone | HCID 68162013 | 75.8% |
Reaction Steps
Synthesis was carried out in the same manner as in Synthesis Method 2 (5) in Reference Synthetic Example 3 by using 4.5 g (0.0176 mol) of 5-(2,3-dihydro-1H-inden-5-yl)-4-methoxythiophene-3-carbonitrile to obtain 3.64 g of the desired product (yield: 75.8%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08889732B2 |
| Source dataset | uspto-grants-2014_11 |
| ORD ID | ord-d50532fc38bd4c5d840ef6f00b06f2cd |
| Source note | uspto-grants-2014_11 |