化工社化工社 化学情報印刷レポート · 研究参考用
HRID 337505作成日：2026年10月26日
Hydroxyamine hydrochloride → N-[4-(2-Furyl)-5-(tetrahydropyran-4-ylcarbonyl)thiazol-2-yl]-5-(hydroxyimino)furan-2-carboxamide
https://huagongshe.com/reaction/337505
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Hydroxyamine hydrochloride | HCID 443297 | — |
| 反応物 | 5-Formyl-N-[4-(2-furyl)-5-(tetrahydropyran-4-ylcarbonyl)thiazol-2-yl]furan-2-carboxamide | HCID 23144705 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | N-[4-(2-Furyl)-5-(tetrahydropyran-4-ylcarbonyl)thiazol-2-yl]-5-(hydroxyimino)furan-2-carboxamide | HCID 86612469 | 86.3% |
反応手順
Compound 513 (2.40 g, 6.00 mmol) was suspended in ethanol (24 mL), and hydroxylamine hydrochloride (438 mg, 6.30 mmol) was added thereto, followed by stirring at 60° C. for 1 hour. The precipitated solid was collected by filtration to afford the entitled Compound 514 (2.09 g, 84%) as a pale brown solid.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US08889718B2 |
|---|
| 出典データセット | uspto-grants-2014_11 |
|---|
| ORD ID | ord-0d044fee5abd4ce3a5e13b791b75241f |
|---|
| 出典メモ | uspto-grants-2014_11 |
|---|
