反应详情

A mixture of 1-chloro-4-(2-methoxyethoxy)-2-methylbenzene (1 eq.) from the previous step, NBS (1.1 eq.) and benzoyl peroxide (0.05 eq.) in CCl4 (0.2 M) was refluxed for 2 h. The volatiles were then removed in vacuo and the resulting residue was suspended in hexanes. The insolubles were removed via filtration and washed further with hexanes. The filtrate was concentrated in vacuo to afford the title compound as a colorless oil.

1. temperaturewas refluxed for 2 h
2. customThe volatiles were then removed in vacuo
3. customThe insolubles were removed via filtration
4. washwashed further with hexanes
5. concentrationThe filtrate was concentrated in vacuo