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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 337736Generated: October 25, 2026

Potassium Carbonate → HCID 89962883, compound

https://huagongshe.com/reaction/337736

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPotassium CarbonateHCID 11430—
Reactant2,4-DifluoropyrimidineHCID 137716—
Reactant3-Fluoro-4-{[(1S*,2R*)-2-(1-methyl-1H-pyrazol-5-yl)cyclopentyl]oxy}benzenesulfonamideHCID 89963259—
SolventDimethylformamideHCID 6228—
ProductHCID 89962883HCID 8996288363%

Reaction Steps

The reaction and aftertreatment were conducted in the same manner as in Example 16d by using 3-fluoro-4-{[(1S*,2R*)-2-(1-methyl-1H-pyrazol-5-yl)cyclopentyl]oxy}benzenesulfonamide (0.10 g, 0.29 mmol) prepared in Example 16c, 2,4-difluoropyrimidine (0.10 g, 0.88 mmol), potassium carbonate (0.16 g, 1.18 mmol) and DMF (3.0 mL), to yield the title compound (56 mg, 63%) as a colorless solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08889741B2
Source datasetuspto-grants-2014_11
ORD IDord-33884d3794204d9ba3c577460bd50909
Source noteuspto-grants-2014_11