Chlorosulfonic acid → HCID 89963304, compound

HRID 337861Notes

Reaction equation

[CH2:1]([C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[F:9])[CH3:2].[S:10]([Cl:14])(=O)(=[O:12])[OH:11]>>[CH2:1]([C:3]1[CH:8]=[C:7]([S:10]([Cl:14])(=[O:12])=[O:11])[CH:6]=[CH:5][C:4]=1[F:9])[CH3:2]

Participants

Reactant 2

HCID 24638Chlorosulfonic acid

HCID 111053611-Ethyl-2-fluorobenzene

Product 1

HCID 89963304HCID 89963304, compound

Procedure

The reaction and aftertreatment were conducted in the same manner as in Example 65a by using 1-ethyl-2-fluorobenzene (2.30 g, 19.0 mmol) and chlorosulfuric acid (4.9 mL, 74.0 mmol), to yield the title compound in a crude form.

Workup

customThe reaction and aftertreatment

Sources & evidence

ORD record: ord-4b1a527cae4549bc97d125106d1249d8
Source dataset: uspto-grants-2014_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08889741B2

Reaction notes

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