HCID 89962390, compound → HCID 89962648, compound

HRID 337939Notes

Reaction equation

HRID 337939 reaction equation
[CH3:1][N:2]1[C:6]([C@H:7]2[CH2:11][CH2:10][CH2:9][C@@H:8]2[OH:12])=[CH:5][CH:4]=[N:3]1>CCCCCC.C(O)C>[CH3:1][N:2]1[C:6]([C@@H:7]2[CH2:11][CH2:10][CH2:9][C@H:8]2[OH:12])=[CH:5][CH:4]=[N:3]1

Participants

3

Reactant 1

HCID 89962390HCID 89962390, compound

Product 1

HCID 89962648HCID 89962648, compound

Reagents, catalysts & solvents 1

HCID 21879635Ethanol hexaneSolvent

Procedure

The (1S*,2R*)-2-(1-methyl-1H-pyrazol-5-yl)cyclopentanol prepared in Example 8a was optically resolved with CHIRALPAK IC (Daicel Corp.; hexane/ethanol=8:2) to yield the title compound as a colorless oil.

Sources & evidence

ORD record
ord-24e56322a90c40d88250c8d58d45913b
Source dataset
uspto-grants-2014_11
Patent number
US08889741B2

Reaction notes

Loading…