HCID 89962427, compound → HCID 89962859, compound

HRID 337958Notes

Reaction equation

HRID 337958 reaction equation
[CH3:1][N:2]1[C:6]([C@H:7]2[CH2:12][CH2:11][CH2:10][CH2:9][C@@H:8]2[OH:13])=[CH:5][CH:4]=[N:3]1>CCCCCC.C(O)C>[CH3:1][N:2]1[C:6]([C@@H:7]2[CH2:12][CH2:11][CH2:10][CH2:9][C@H:8]2[OH:13])=[CH:5][CH:4]=[N:3]1

Participants

3

Reactant 1

HCID 89962427HCID 89962427, compound

Product 1

HCID 89962859HCID 89962859, compound

Reagents, catalysts & solvents 1

HCID 21879635Ethanol hexaneSolvent

Procedure

The (1S*,2R*)-2-(1-methyl-1H-pyrazol-5-yl)cyclohexanol prepared in Example 4a was optically resolved with CHIRALPAK IB (Daicel Corp.; hexane/ethanol=9:1) to yield the title compound as a colorless oil.

Sources & evidence

ORD record
ord-42716c07dab34899b932347ccd36a013
Source dataset
uspto-grants-2014_11
Patent number
US08889741B2

Reaction notes

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