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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 338006Generated: October 30, 2026

Tetrabutylammonium Fluoride → HCID 89963043, compound

https://huagongshe.com/reaction/338006

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrabutylammonium FluorideHCID 2724141—
ReactantHCID 89962847HCID 89962847—
SolventTetrahydrofuranHCID 8028—
ProductHCID 89963043HCID 8996304392%

Reaction Steps

The reaction and aftertreatment were conducted in the same manner as in Example 120c by using the (1S*,2R*,4R*)-4-{[tert-butyl(dimethyl)silyl]oxy}-2-(1-methyl-1H-pyrazol-5-yl)cyclohexyl benzoate (1.30 g, 3.14 mmol) prepared in Example 162a, tetrabutyl ammonium fluoride (1.0 M solution in THF; 9.42 mL, 9.42 mmol) and THF (5.0 mL), to yield the title compound (867 mg, 92%) as a colorless oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08889741B2
Source datasetuspto-grants-2014_11
ORD IDord-d1e553ea89ad44209122ad74ca87503c
Source noteuspto-grants-2014_11