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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 338013Generated: October 29, 2026

Tetrabutylammonium Fluoride → HCID 89963558, compound

https://huagongshe.com/reaction/338013

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrabutylammonium FluorideHCID 2724141—
ReactantHCID 89963263HCID 89963263—
SolventTetrahydrofuranHCID 8028—
ProductHCID 89963558HCID 8996355897%

Reaction Steps

The reaction and aftertreatment were conducted in the same manner as in Example 120c by using the (1S*,2R*,5R*)-5-{[tert-butyl(dimethyl)silyl]oxy}-2-(1-methyl-1H-pyrazol-5-yl)cyclohexyl benzoate (739 mg, 1.78 mmol) prepared in Example 163a, tetrabutyl ammonium fluoride (1.0 M solution in THF; 5.34 mL, 5.34 mmol) and THF (5.0 mL), to yield the title compound (517 mg, 97%) as a colorless solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08889741B2
Source datasetuspto-grants-2014_11
ORD IDord-532a8e4d55a84f7bbd15eab75e3dbf6f
Source noteuspto-grants-2014_11