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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 33829Generated: October 25, 2026

2,2,2-Trifluoroethylhydrazine → Pde10-IN-5

https://huagongshe.com/reaction/33829

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,2,2-TrifluoroethylhydrazineHCID 78740—
Reactant2-((4-(1-methyl-4-pyridin-4-yl-1H-pyrazol-3-yl)phenoxy)methyl)quinolineHCID 11581936—
ProductPde10-IN-5HCID 11554381—

Reaction Steps

Following the procedure for the preparation of 2-[4-(1-Methyl-4-pyridin4-yl-1H-pyrazol-3-yl)-phenoxymethyl]-quinoline but substituting (2,2,2-trifluoro-ethyl)-hydrazine provided the title compound. MS: (M+H m/z=461.2).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07429665B2
Source datasetuspto-grants-2008_09
ORD IDord-c3cb290b15a94b93b24ba62078717c3e
Source noteuspto-grants-2008_09