HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-(4-chlorophenyl)-3,4-dihydro-2H-pyran → 3-(4-chlorophenyl)tetrahydro-2H-pyran
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-(4-chlorophenyl)-3,4-dihydro-2H-pyran | HCID 86698859 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Platinum oxide (PtO) | HCID 82844 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | 3-(4-chlorophenyl)tetrahydro-2H-pyran | HCID 86698860 | 96.3% |
Reaction Steps
To a solution of 5-(4-chlorophenyl)-3,4-dihydro-2H-pyran (350 mg, 1.80 mmol) in ethyl acetate (8 mL) was added platinum oxide (41 mg, 0.18 mmol) and the reaction was charged with a hydrogen ballon and stirred at room temperature for 6 hours. The reaction was filtered, and the filtrate was evaporated to give crude title compound (340 mg, 96.3%) as white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08889730B2 |
| Source dataset | uspto-grants-2014_11 |
| ORD ID | ord-ad21d61a0f6e4810a60ea3fe1bdac0de |
| Source note | uspto-grants-2014_11 |