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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 338541Generated: October 29, 2026

5-(4-chlorophenyl)-3,4-dihydro-2H-pyran → 3-(4-chlorophenyl)tetrahydro-2H-pyran

https://huagongshe.com/reaction/338541

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-(4-chlorophenyl)-3,4-dihydro-2H-pyranHCID 86698859—
ReactantHCID 178418361HCID 178418361—
CatalystPlatinum oxide (PtO)HCID 82844—
SolventEthyl AcetateHCID 8857—
Product3-(4-chlorophenyl)tetrahydro-2H-pyranHCID 8669886096.3%

Reaction Steps

To a solution of 5-(4-chlorophenyl)-3,4-dihydro-2H-pyran (350 mg, 1.80 mmol) in ethyl acetate (8 mL) was added platinum oxide (41 mg, 0.18 mmol) and the reaction was charged with a hydrogen ballon and stirred at room temperature for 6 hours. The reaction was filtered, and the filtrate was evaporated to give crude title compound (340 mg, 96.3%) as white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08889730B2
Source datasetuspto-grants-2014_11
ORD IDord-ad21d61a0f6e4810a60ea3fe1bdac0de
Source noteuspto-grants-2014_11