4-Aminobenzoic Acid → HCID 61180965, compound

Participants

Reaction Steps

N,N-carbonyldiimidazole (1.62 g, 10 mmol), benzyl amine (1.07 g, 10 mmol), p-aminobenzoic acid (1.52 g, 10 mmol), and 10 ml of 1 mol/L sodium hydroxide solution are used according to the method for the production of compound III in Method two to obtain 2.65 g of 4-[(3-benzylureido)methyl]benzoic acid (intermediate M-32) as a white solid, with a yield of 93.0%.

Provenance & Evidence