4-Aminobenzoic Acid → HCID 67078816, compound

Participants

Reaction Steps

N,N-carbonyldiimidazole (1.62 g, 10 mmol), p-methyl benzyl amine (1.21 g, 10 mmol), p-aminobenzoic acid (1.52 g, 10 mmol), and 10 ml of 1 mol/L sodium hydroxide solution are used according to the method for the production of compound III in Method two to obtain 2.83 g of 4-[(4-methylbenzylureido)methyl]benzoic acid (intermediate M-33) as a white solid, with a yield of 95.0%.

Provenance & Evidence