4-Aminobenzoic Acid → HCID 67079226, compound

Participants

Reaction Steps

N,N-carbonyldiimidazole (1.62 g, 10 mmol), 4-nitrobenzyl amine (1.52 g, 10 mmol), p-aminobenzoic acid (1.52 g, 10 mmol), and 10 ml of 1 mol/L sodium hydroxide solution are used according to the method for the production of compound III in Method two to obtain 2.49 g of 4-[(4-nitrobenzylureido)methyl]benzoic acid (intermediate M-36) as a yellow solid, with a yield of 75.4%.

Provenance & Evidence