4-Aminobenzoic Acid → HCID 61200356, compound

Participants

Reaction Steps

N,N-carbonyldiimidazole (1.62 g, 10 mmol), 3-aminomethylpyridine (1.08 g, 10 mmol), p-aminobenzoic acid (1.52 g, 10 mmol), and 10 ml of 1 mol/L sodium hydroxide solution are used according to the method for the production of compound III in Method two to obtain 2.65 g of 4-[(3-pyridylmethylureido)methyl]benzoic acid (intermediate M-38) as a white solid, with a yield of 93.3%. MS(ES+):m/e 286.13.

Provenance & Evidence