2-(Pyridin-4-yl)-1-(4-(quinolin-2-ylmethoxy)phenyl)ethan-1-one → 2-Pyridin-4-yl-1-[4-(2-quinolin-2-yl-ethyl)-phenyl]-ethanone

HRID 33867Notes

Reaction equation

HRID 33867 reaction equation
[N:1]1[CH:6]=[CH:5][C:4]([CH2:7][C:8]([C:10]2[CH:15]=[CH:14][C:13](OCC3C=CC4C(=CC=CC=4)N=3)=[CH:12][CH:11]=2)=[O:9])=[CH:3][CH:2]=1.CON(C)C(=O)C1C=CC([CH2:38][CH2:39][C:40]2[CH:49]=[CH:48][C:47]3[C:42](=[CH:43][CH:44]=[CH:45][CH:46]=3)[N:41]=2)=CC=1>>[N:1]1[CH:2]=[CH:3][C:4]([CH2:7][C:8]([C:10]2[CH:11]=[CH:12][C:13]([CH2:38][CH2:39][C:40]3[CH:49]=[CH:48][C:47]4[C:42](=[CH:43][CH:44]=[CH:45][CH:46]=4)[N:41]=3)=[CH:14][CH:15]=2)=[O:9])=[CH:5][CH:6]=1

Participants

3

Reactant 2

HCID 336797272-(Pyridin-4-yl)-1-(4-(quinolin-2-ylmethoxy)phenyl)ethan-1-oneHCID 86249320N-Methoxy-N-methyl-4-(2-quinolin-2-yl-ethyl)-benzamide

Product 1

HCID 685764722-Pyridin-4-yl-1-[4-(2-quinolin-2-yl-ethyl)-phenyl]-ethanone

Procedure

Following the procedure for the preparation of 2-pyridin-4-yl-1-[4-(quinolin-2-ylmethoxy)-phenyl]-ethanone but substituting N-Methoxy-N-methyl-4-(2-quinolin-2-yl-ethyl)-benzamide provided the title compound. MS: (M+H m/z=353.1).

Sources & evidence

ORD record
ord-5802ed2805c54d4ab5cce6931a18d105
Source dataset
uspto-grants-2008_09
Patent number
US07429665B2

Reaction notes

Loading…