HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(Methylthio)-5,6,7,8-tetrahydropyrido[4,3-D]pyrimidine → N-(3-Isopropyl-phenyl)-2-(2-methylsulfanyl-7,8-dihydro-5H-pyrido[4,3-d]pyrimidin-6-yl)-isonicotinamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(Methylthio)-5,6,7,8-tetrahydropyrido[4,3-D]pyrimidine | HCID 55263670 | — |
| Reactant | 2-Bromo-N-(3-isopropyl-phenyl)-isonicotinamide | HCID 86695843 | — |
| Product | N-(3-Isopropyl-phenyl)-2-(2-methylsulfanyl-7,8-dihydro-5H-pyrido[4,3-d]pyrimidin-6-yl)-isonicotinamide | HCID 86695848 | — |
Reaction Steps
In a manner similar to that described for Example 138, 2-(methylsulfanyl)-5,6,7,8-tetrahydropyrido[4,3-d]-pyrimidine and 2-bromo-N-(3-isopropyl-phenyl)-isonicotinamide were converted to the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08889870B2 |
| Source dataset | uspto-grants-2014_11 |
| ORD ID | ord-bcffc46ddc3746528c6f4c3988834517 |
| Source note | uspto-grants-2014_11 |