HCID 17197565, compound → HCID 71735692, compound

HRID 338744Notes

Reaction equation

HRID 338744 reaction equation
[CH3:1][S:2][C:3]1[N:4]=[CH:5][C:6]2[CH2:12][NH:11][CH2:10][CH2:9][C:7]=2[N:8]=1.Br[C:14]1[CH:15]=[C:16]([CH:30]=[CH:31][C:32]=1[CH3:33])[C:17]([NH:19][C:20]1[CH:25]=[CH:24][CH:23]=[C:22]([C:26]([F:29])([F:28])[F:27])[CH:21]=1)=[O:18]>>[CH3:33][C:32]1[CH:14]=[CH:15][C:16]([C:17]([NH:19][C:20]2[CH:25]=[CH:24][CH:23]=[C:22]([C:26]([F:27])([F:29])[F:28])[CH:21]=2)=[O:18])=[CH:30][C:31]=1[N:11]1[CH2:10][CH2:9][C:7]2[N:8]=[C:3]([S:2][CH3:1])[N:4]=[CH:5][C:6]=2[CH2:12]1

Participants

3

Reactant 2

HCID 17197565HCID 17197565, compoundHCID 552636702-(Methylthio)-5,6,7,8-tetrahydropyrido[4,3-D]pyrimidine

Product 1

HCID 71735692HCID 71735692, compound

Procedure

In a manner similar to that described for Example 138, 2-(methylsulfanyl)-5,6,7,8-tetrahydropyrido[4,3-d]-pyrimidine and 3-bromo-4-methyl-N-[3-(trifluoromethyl)phenyl]benzamide were converted to the title compound.

Sources & evidence

ORD record
ord-0dbc6fa07e4b4b118629c5e4469ad6ff
Source dataset
uspto-grants-2014_11
Patent number
US08889870B2

Reaction notes

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