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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 33880Generated: October 27, 2026

2-(Pyridin-4-yl)-1-(4-(quinolin-2-ylmethoxy)phenyl)ethan-1-one → 1-[3-Chloro-4-(quinolin-2-ylmethoxy)-phenyl]-2-pyridin-4-yl-ethanone

https://huagongshe.com/reaction/33880

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(Pyridin-4-yl)-1-(4-(quinolin-2-ylmethoxy)phenyl)ethan-1-oneHCID 33679727—
Reactant3-Chloro-N-methoxy-N-methyl4-(quinolin-2-ylmethoxy)-benzamideHCID 86249347—
Product1-[3-Chloro-4-(quinolin-2-ylmethoxy)-phenyl]-2-pyridin-4-yl-ethanoneHCID 68576300—

Reaction Steps

Following the procedure for the preparation of 2-pyridin-4-yl-1-[4-(quinolin-2-ylmethoxy)-phenyl]-ethanone but substituting 3-Chloro-N-methoxy-N-methyl-4-(quinolin-2-ylmethoxy)-benzamide provided the title compound. (M+H m/z=389.0).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07429665B2
Source datasetuspto-grants-2008_09
ORD IDord-5e86205749a6458a80277b4e27cc3a64
Source noteuspto-grants-2008_09