反应详情

Following the procedure for the preparation of 2-[4-(5-Pyridin-4-yl-[1,2,4]triazol-1-yl)-phenoxymethyl]-quinoline but substituting 4-(Quinolin-2-ylmethoxy)-benzamide, Pyridin4-yl-hydrazine and N,N-dimethylacetamide dimethyl acetal provided the title compound. 1H NMR (400 MHz, CDCl3) δ 8.61 (d, J=6.2 Hz, 2 H), 8.21 (d, J=8.7 Hz, 1 H), 8.07 (d, J=7.9 Hz, 1H, 7.83 (d, J=8.3 Hz, 1H), 7.75 (m, 1 H), 7.64 (d, J=8.3 Hz, 1 H), 7.55 (m, 1 H), 7.56 (m, 1H), 7.41 (d, J=9.1 Hz, 2 H), 7.29 (d, J=6.2 Hz, 2H), 7.05 (d, J=8.7 Hz, 2H), 5.40 (s, 2H), 2.47 (s, 3H); MS: (M+H m/z=394.3).