Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 33892Generated: October 28, 2026

4-[3-(4-Benzyloxy-phenyl)-1-(2,2,2-trifluoro-ethyl)-1H-pyrazol-4-yl]-pyridine → 4-[4-Pyridin-4-yl-1-(2,2,2-trifluoro-ethyl)-1H-pyrazol-3-yl]-phenol

https://huagongshe.com/reaction/33892

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-[3-(4-Benzyloxy-phenyl)-1-(2,2,2-trifluoro-ethyl)-1H-pyrazol-4-yl]-pyridineHCID 53465551—
Reactant4-[1-methyl-4-(4-pyridinyl)-1H-pyrazol-3-yl]PhenolHCID 135915213—
Product4-[4-Pyridin-4-yl-1-(2,2,2-trifluoro-ethyl)-1H-pyrazol-3-yl]-phenolHCID 136000177—

Reaction Steps

Following the procedure for the preparation of 4-(1-Methyl4-pyridin4-yl-1H-pyrazol-3-yl)-phenol but substituting 4-[3-(4-Benzyloxy-phenyl)-1-(2,2,2-trifluoro-ethyl)-1H-pyrazol-4-yl]-pyridine provided the title compound. MS: (M+H m/z=320.1)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07429665B2
Source datasetuspto-grants-2008_09
ORD IDord-b0030006b24e433e98d55e73f23b15f2
Source noteuspto-grants-2008_09