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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 33895Generated: October 26, 2026

Benzyl Bromide → Benzyl 4-benzyloxy-2-fluorobenzoate

https://huagongshe.com/reaction/33895

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzyl BromideHCID 7498—
Reactant2-Fluoro-4-hydroxybenzoic AcidHCID 2783398—
ReactantMethyl 4-(2-quinolinylmethoxy)benzoateHCID 19934817—
ProductBenzyl 4-benzyloxy-2-fluorobenzoateHCID 57916590—

Reaction Steps

Following the procedure for the preparation of 4-(Quinolin-2-ylmethoxy)-benzoic acid methyl ester but substituting two equivalents of benzyl bromide and 2-Fluoro4-hydroxy-benzoic acid provided the title compound. MS: (M+H m/z=337.2).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07429665B2
Source datasetuspto-grants-2008_09
ORD IDord-1a5c99359f244509a88127ccbce3db88
Source noteuspto-grants-2008_09