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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 33897Generated: October 26, 2026

4-(Benzyloxy)-2-fluorobenzoic acid → 4-Benzyloxy-2-fluoro-N-methoxy-N-methyl-benzamide

https://huagongshe.com/reaction/33897

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(Benzyloxy)-2-fluorobenzoic acidHCID 22314502—
ReactantBenzamide, N-methoxy-N-methyl-4-(2-quinolinylmethoxy)-HCID 44234674—
Product4-Benzyloxy-2-fluoro-N-methoxy-N-methyl-benzamideHCID 86249234—

Reaction Steps

Following the procedure for the preparation of N-Methoxy-N-methyl4-(quinolin-2-ylmethoxy)-benzamide but substituting 4-Benzyloxy-2-fluoro-benzoic acid provided the title compound. MS: (M+H m/z=290.2).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07429665B2
Source datasetuspto-grants-2008_09
ORD IDord-c1f7b80577c4444990715f2175634604
Source noteuspto-grants-2008_09