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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 33898Generated: October 29, 2026

2-(Pyridin-4-yl)-1-(4-(quinolin-2-ylmethoxy)phenyl)ethan-1-one → 1-(4-Benzyloxy-2-fluoro-phenyl)-2-pyridin-4-yl-ethanone

https://huagongshe.com/reaction/33898

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(Pyridin-4-yl)-1-(4-(quinolin-2-ylmethoxy)phenyl)ethan-1-oneHCID 33679727—
Reactant4-Benzyloxy-2-fluoro-N-methoxy-N-methyl-benzamideHCID 86249234—
Product1-(4-Benzyloxy-2-fluoro-phenyl)-2-pyridin-4-yl-ethanoneHCID 68578940—

Reaction Steps

Following the procedure for the preparation of 2-pyridin-4-yl-1-[4-(quinolin-2-ylmethoxy)-phenyl]-ethanone but substituting 4-Benzyloxy-2-fluoro-N-methoxy-N-methyl-benzamide provided the title compound. MS: (M+H m/z=322.1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07429665B2
Source datasetuspto-grants-2008_09
ORD IDord-adcb5289bde44e6190c4869450bfc34c
Source noteuspto-grants-2008_09