1-(4-Benzyloxy-2-fluoro-phenyl)-2-pyridin-4-yl-ethanone → HCID 178505957, compound

HRID 33901Notes

Reaction equation

HRID 33901 reaction equation
N1C=CC(C2[C:8](C3C=CC(OCC4C=CC5C(=CC=CC=5)N=4)=CC=3)=[N:9][NH:10]C=2)=CC=1.[CH2:30]([O:37][C:38]1[CH:43]=[CH:42][C:41]([C:44](=O)[CH2:45][C:46]2[CH:51]=[CH:50][N:49]=[CH:48][CH:47]=2)=[C:40]([F:53])[CH:39]=1)[C:31]1[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=1>>[CH2:30]([O:37][C:38]1[CH:43]=[CH:42][C:41]([C:44]2[C:45]([C:46]3[CH:51]=[CH:50][N:49]=[CH:48][CH:47]=3)=[CH:8][NH:9][N:10]=2)=[C:40]([F:53])[CH:39]=1)[C:31]1[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=1

Participants

3

Reactant 2

HCID 685789401-(4-Benzyloxy-2-fluoro-phenyl)-2-pyridin-4-yl-ethanoneHCID 178419992HCID 178419992, compound

Product 1

HCID 178505957HCID 178505957, compound

Procedure

Following the procedure for the preparation of 2-[4-(4-Pyridin4-yl-1H-pyrazol-3-yl)-phenoxymethyl]-quinoline but substituting 1-(4-Benzyloxy-2-fluoro-phenyl)-2-pyridin-4-yl-ethanone provided the title compound. MS: (M+H m/z=346.3).

Sources & evidence

ORD record
ord-04566e18fd6d4401af912cfcc1541650
Source dataset
uspto-grants-2008_09
Patent number
US07429665B2

Reaction notes

Loading…