1-(4-Benzyloxy-phenyl)-2-pyridin-4-yl-ethanone → 2-Pyridin-4-yl-1-(4-triisopropylsilanyloxymethyl-phenyl)-ethanone

HRID 33910Notes

Reaction equation

HRID 33910 reaction equation
C(O[C:9]1[CH:14]=[CH:13][C:12]([C:15](=[O:23])[CH2:16][C:17]2[CH:22]=[CH:21][N:20]=[CH:19][CH:18]=2)=[CH:11][CH:10]=1)C1C=CC=CC=1.CON(C)C(=O)C1C=CC([CH2:34][O:35][Si:36]([CH:43]([CH3:45])[CH3:44])([CH:40]([CH3:42])[CH3:41])[CH:37]([CH3:39])[CH3:38])=CC=1>>[N:20]1[CH:19]=[CH:18][C:17]([CH2:16][C:15]([C:12]2[CH:11]=[CH:10][C:9]([CH2:34][O:35][Si:36]([CH:37]([CH3:39])[CH3:38])([CH:43]([CH3:45])[CH3:44])[CH:40]([CH3:42])[CH3:41])=[CH:14][CH:13]=2)=[O:23])=[CH:22][CH:21]=1

Participants

3

Reactant 2

HCID 109027571-(4-Benzyloxy-phenyl)-2-pyridin-4-yl-ethanoneHCID 86249259N-Methoxy-N-methyl-4-triisopropylsilanyloxymethyl-benzamide

Product 1

HCID 685761892-Pyridin-4-yl-1-(4-triisopropylsilanyloxymethyl-phenyl)-ethanone

Procedure

Following the procedure for the preparation of 1-(4-Benzyloxy-phenyl)-2-pyridin-4-yl-ethanone but substituting N-Methoxy-N-methyl-4-triisopropylsilanyloxymethyl-benzamide provided the title compound. MS: (M+H m/z=384.1).

Sources & evidence

ORD record
ord-ee99702c564c40a69a6fb9616c81b69c
Source dataset
uspto-grants-2008_09
Patent number
US07429665B2

Reaction notes

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