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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 339107Generated: October 30, 2026

Hydrochloric Acid → HCID 86653070, compound

https://huagongshe.com/reaction/339107

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 86653071HCID 86653071—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
ProductHCID 86653070HCID 86653070—

Reaction Steps

A solution of 5-cyano-N-{2,2,2-trifluoro-1-[3-(trifluoromethyl)phenyl]ethyl}-1-benzofuran-2-carboxamide (273 mg, 0.66 mmol) in methanol (10 ml) was admixed with concentrated hydrochloric acid (0.42 ml) and palladium on carbon (10%; 50 mg) and stirred under a hydrogen atmosphere for 2 h. The reaction mixture was then filtered through Celite® and a silica gel pad.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08889878B2
Source datasetuspto-grants-2014_11
ORD IDord-0ec295aeb6d946c4961573d21a344fb5
Source noteuspto-grants-2014_11