HCID 72705162, compound → HCID 86705886, compound

Participants

Reaction Steps

Following a procedure analogous to that for the synthesis of Compound G of Example 1, (S)-tert-butyl 3-(((R)-1,2,3,4-tetrahydronaphthalen-1-yl)carbamoyl)-7-((3R,5S)-5-(((R)-1,2,3,4-tetrahydronaphthalen-1-yl)carbamoyl)pyrrolidin-3-yl)-3,4-dihydroisoquinoline-2(1H)-carboxylate (97 mg, 0.15 mmol) was converted to the title compound (82 mg, 100%). MS (ESI+) m/z 549.2 (M+H)+.

Provenance & Evidence