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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 339321Generated: October 25, 2026

1,3-Benzodioxole-5-carboxylic acid → (R)-methyl 2-(benzo[d][1,3]dioxole-6-carboxamido)-3-methylbutanoate

https://huagongshe.com/reaction/339321

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,3-Benzodioxole-5-carboxylic acidHCID 7196—
Reactant(R)-methyl 2-amino-3-methylbutanoateHCID 2305648—
Product(R)-methyl 2-(benzo[d][1,3]dioxole-6-carboxamido)-3-methylbutanoateHCID 5752794850%

Reaction Steps

Prepared in a similar manner to example 4 using benzo[d][1,3]dioxole-5-carboxylic acid and (R)-methyl 2-amino-3-methylbutanoate. Yield: 50%. MS (M+H, 280.1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08895050B2
Source datasetuspto-grants-2014_11
ORD IDord-e0df286839f64668bbbae323e3ad6fef
Source noteuspto-grants-2014_11